Tuesday, July 13, 2010
Stem cell transplantation is used to treat cancer and other illnesses, and it is a prolonged and physically demanding process that often causes children and their families high levels of distress, the authors of the study noted. Previous studies have shown that complementary therapies, such as hypnosis and massage, can sometimes help adult patients cope with stem cell transplantation.
The results of the new U.S. study, which included 178 children undergoing stem cell transplantation at four medical centers, were released online July 12 in advance of publication in an upcoming print issue of the journal Cancer.
The participants were randomly assigned to different groups, including: a child-targeted intervention involving massage and humor therapy; the same child intervention program plus a parent intervention program involving massage and relaxation/imagery; or standard care.
The intervention programs began upon hospital admission and continued through the third week of the stem cell transplantation treatment. The children and their parents were evaluated for distress and mood problems each week from the time of admission through the sixth week.
The complementary therapies didn't produce significant benefits for the children, the study authors found. And although this finding doesn't prove that the interventions don't work, the results do raise questions about the benefits of such therapies for children undergoing stem cell transplantation, team leader Sean Phipps of St. Jude Children's Research Hospital in Memphis noted in a news release from the journal's publisher.
Overall, the levels of distress among the children undergoing stem cell transplantation were low, the researchers added, which suggests that they likely do well with standard supportive care.
Friday, July 2, 2010
Disorders that start when you're young, in adolescence, no matter what the disorder, are always harder to treat and harder to recover from," said Dr. David Schlager, a clinical assistant professor of psychiatry and behavioral science at Texas A&M Health Science Center College of Medicine.
This applies both to a wide range of problems, he said, from eating disorders such as bulimia and anorexia, to addictions and mental illness.
No one knows exactly why this is so, in terms of brain chemistry, but adolescence can be hard enough even without these complications.
"There are so many crucial things going on, so much pressure to establish yourself in various ways," explained Schlager, who's also a psychiatrist with Lone Star Circle of Care. Mental health can be easier for adults, he reasoned, because "if you've made it to 30 you've carved out a little groove for yourself, most people will give you a little latitude."
Also, the bodies and minds of people suffering from any of these disorders work differently than those of healthy individuals, making the challenge even tougher.
"In anorexia, [which typically sets in between the ages of 14 and 17], when someone is severely underweight, their brain and their body tend to react differently," said Andrea Vazzana, a clinical assistant professor of child and adolescent psychiatry at New York University Child Study Center. "Someone who is severely underweight is likely to have difficulty concentrating, making good judgments. Reasoning becomes more difficult and their mood is affected. They're more irritable and depressed and anxious."
People with bulimia suffer from a similar problem. "They're binging and purging and their body is affected. They have the same preoccupation with weight [as anorexics] and, to a lesser extent than with anorexia, their judgment is impacted," Vazzana said.
But clinicians are at a disadvantage when it comes to treating troubled teens, because there's a dearth of research into what treatments actually work for the younger people.
For example, "there aren't a lot of treatments [for eating disorders], especially in adolescence, that have been proven to work," Vazzana said. Family therapy is one treatment that has shown good results in randomized, controlled trials.
There are good treatments that work for bulimia in adults but no one knows if they trickle down to children, though anecdotally they do seem to have some effect, Vazzana said. These include cognitive behavioral therapy and interpersonal therapy.
None of this means that parents should give up hope. Treating eating disorders, addictions and other mental health issues in younger people can be difficult, but it's not impossible, said Schlager.
"It depends on the condition. If it's one of the conditions that only have behavioral treatments and no medication, then it's hard first of all to get them [children] to participate in behavioral treatment," he said.
And, according to Vazzana, there's no evidence yet that 12-Step programs work for eating disorders, especially in younger people, because they require people to acknowledge their illness.
"To get a teenager to acknowledge that they have an illness and that they need care, that's narcissistically overwhelming," Schlager said. "Like most young people, they pretend it's not happening."
Wynn Oleson is a pseudonym for the author of My Daughter Is Bulimic and the Cat Has Hairballs: The 95-Pound Addict in the Room. She found that neither 12-Step programs for addiction, nor a host of other "adult-oriented" treatments, helped her daughter, who has struggled with both eating disorders and addiction.
"As a young girl, she was treated like anybody who showed similar symptoms -- meaning adults," Oleson recalled. "In the rehab center, her roommates were 35 or 40 years old. She was placed with hardened heroin addicts who had been in prison. They're not bad people. But they are very deep into their addiction and their stories to a young, impressionable girl from a very different background who has not lived that life, it's all pretty exciting stuff."